Program Information
The College of Pharmacy offers the Doctor of Philosophy degree in Pharmaceutical Sciences with a concentration in Medicinal Chemistry. Medicinal chemistry is a unique blend of the physical and biological sciences. The scope of the field is sufficiently broad to give students with many different science backgrounds a rewarding and challenging program of study. Areas of active research include organic synthesis of medicinal agents, metal chelate design, prodrugs and topical drug delivery, drug metabolism, molecular toxicology, molecular biology, combinatorial chemistry, neurochemistry, analytical chemistry, molecular modeling, natural products, and drug discovery.
The College also offers the Master of Science in Pharmacy degree in Pharmaceutical Sciences (non-thesis option) with concentrations in both forensic drug chemistry and forensic serology and DNA in a distance learning format. Minimum requirements for the M.S.P. and Ph.D. degrees are described in the Graduate Degrees section of this catalog.
The applicant should have an undergraduate degree in pharmacy, chemistry, biology, or premedical sciences. A background in calculus and physical and organic chemistry is required. In addition to graduate medicinal chemistry courses in the College of Pharmacy, graduate courses in chemistry and biochemistry are required for the program.
For more information, please see our websites: http://pharmacy.ufl.edu/education/graduate-programs and http://pharmacy.ufl.edu/mc
Degrees Offered With a Major in Pharmaceutical Sciences
- Doctor of Philosophy
- concentration in Medicinal Chemistry
- optional second concentration in Clinical and Translational Science
- concentration in Toxicology
- concentration in Medicinal Chemistry
- Master of Science in Pharmacy
- concentration in Clinical Toxicology
- concentration in Forensic Drug Chemistry
- concentration in Forensic Serology and DNA
- concentration in Forensic Science
- concentration in Medicinal Chemistry
- concentration in Pharmaceutical Chemistry
Requirements for these degrees are given in the Graduate Degrees section of this catalog.
Medicinal Chemistry Courses
| Code | Title | Credits |
|---|---|---|
| PHA 6354 | Natural Medicinal Products | 3 |
| PHA 6356 | Structure Determination of Complex Natural Products | 3 |
| PHA 6357 | Herbal & Dietary Supplements | 3 |
| PHA 6417 | Pharmaceutical Analysis II | 3 |
| PHA 6425 | Drug Biotrans and Molecular Mechanisms of Toxicity | 3 |
| PHA 6432 | Fundamentals of Pharmaceutical Chemistry | 1 |
| PHA 6435 | Biosynthetic Logic of Medicinal Natural Products | 3 |
| PHA 6444 | Pharmaceutical Chemistry I | 3 |
| PHA 6447 | Drug Design | 3 |
| PHA 6448 | High Throughput Drug Discovery | 2 |
| PHA 6471 | Synthetic Medicinal Chemistry | 3 |
| PHA 6472 | Organic Synthesis of Drug Molecules | 3 |
| PHA 6476 | Advanced Combinatorial Chemistry in Drug Discovery | 3 |
| PHA 6534 | Toxicology of Chemical Weapons | 3 |
| PHA 6535 | Principles of Nucleotide Activity | 2 |
| PHA 6543 | Pharmaceutical Chemistry II | 3 |
| PHA 6556 | Introduction to Clinical Toxicology | 3 |
| PHA 6557 | Clinical Toxicology 1 | 3 |
| PHA 6840 | Medicinal Chemistry of Drugs of Abuse | 3 |
| PHA 6850 | Principles of Forensic Science | 3 |
| PHA 6851 | Forensic Analysis of DNA | 3 |
| PHA 6853 | Biological Evidence and Serology | 3 |
| PHA 6854 | Forensic Immunology | 3 |
| PHA 6855 | Forensic Genetics | 3 |
| PHA 6856 | Blood Spatter and Distribution | 3 |
| PHA 6905C | Research Procedures in Medicinal Chemistry | 1-4 |
| PHA 6934 | Seminar in Medicinal Chemistry | 1 |
| PHA 6852 | Mammalian Molecular Biology | 3 |
| VME 6602 | General Toxicology | 3 |
| VME 6605 | Toxic Substances | 3 |
| VME 6613 | Forensic Toxicology I | 3 |
| VME 6614 | Forensic Toxicology II | 3 |
| VME 6650 | Principles of Mammalian Pharmacology | 4 |
| VME 6766 | Laboratory Quality Assurance/Quality Control | 3 |
Pharmaceutical Outcomes and Policy Courses
| Code | Title | Credits |
|---|---|---|
| PHA 5270 | Health Care and Patient Safety | 3 |
| PHA 5271 | Health Care Risk Management | 3 |
| PHA 5272 | 3 | |
| PHA 6206 | 3 | |
| PHA 6227 | Institutional Pharmacy Leadership I | 3 |
| PHA 6228 | Institutional Pharmacy Leadership II | 3 |
| PHA 6235 | 2 | |
| PHA 6250 | Patient Responsibility in Health Care | 3 |
| PHA 6254 | Structure, Process and Outcomes of Regulation II | 2 |
| PHA 6264 | Pharmacoeconomics and Health Technology Assessment | 3 |
| PHA 6265 | Introduction to Pharmaceutical Outcomes and Policy I | 3 |
| PHA 6266 | Introduction to Pharmaceutical Outcomes and Policy II | 2 |
| PHA 6268 | Pharmacoepidemiology and Patient Safety | 3 |
| PHA 6269 | Pharmaceutical Products and Public Policy | 3 |
| PHA 6273 | Structure, Process and Outcomes of Regulation I | 2 |
| PHA 6274 | Federal Regulations of Drugs and Pharmacy | 3 |
| PHA 6275 | Federal Regulations of Controlled Substances | 3 |
| PHA 6276 | Pharmacy Benefit Design & Management | 3 |
| PHA 6277 | Ethics in Drug Development Production and Use | 3 |
| PHA 6278 | State Regulation of Drugs and Pharmacy | 3 |
| PHA 6279 | Pharmaceutical Outcomes and Policy Seminar | 1 |
| PHA 6280 | Medicare and Medicaid | 3 |
| PHA 6281 | Practices and Procedures of Administrative Agencies | 3 |
| PHA 6283 | Commercial Applications of Pharmacoeconomics | 3 |
| PHA 6286 | Pharmaceutical Microeconomics | 3 |
| PHA 6287 | Pharmaceutical Health Economics | 3 |
| PHA 6288 | Critical Review of Research Methods | 3 |
| PHA 6289 | Regulating Clinical Research | 3 |
| PHA 6290 | Pharmaceutical Fraud and Abuse | 3 |
| PHA 6291 | Pharmaceutical Health Care Systems | 3 |
| PHA 6472 | Organic Synthesis of Drug Molecules | 3 |
| PHA 6476 | Advanced Combinatorial Chemistry in Drug Discovery | 3 |
| PHA 6717 | Measurement in Pharmaceutical Outcomes and Policy Research | 3 |
| PHA 6793 | Evidentiary Basis of Pharmaceutical Use | 3 |
| PHA 6796 | Study Design in Pharmaceutical Outcomes & Policy Research | 3 |
| PHA 6798 | The Use and Abuse of Statistics in Drug Regulation | 3 |
| PHA 6799 | Patient Safety Program Evaluation | 3 |
| PHA 6805 | Applied Data Interpretation and Reporting of Findings in Pharmacy | 3 |
| PHA 6860 | 3 | |
| PHA 6891 | Introduction to Pharmacoepidemiology | 3 |
| PHA 6892 | Practices and Procedures of the IRB | 3 |
| PHA 6893 | Research Ethics | 3 |
| PHA 6899 | Advanced OB/GYN and Pediatric Pharmacoepidemiology | 3 |
| PHA 6937 | Topics in Pharmaceutical Administration | 2 |
Pharmacodynamics Courses
| Code | Title | Credits |
|---|---|---|
| PHA 6472 | Organic Synthesis of Drug Molecules | 3 |
| PHA 6476 | Advanced Combinatorial Chemistry in Drug Discovery | 3 |
| PHA 6508 | Systems Physiology and Pathophysiology I | 5 |
| PHA 6509 | Systems Physiology and Pathophysiology II | 5 |
| PHA 6512L | Experiential Research Training in Pharmacodynamics | 1-4 |
| PHA 6521C | Research Techniques in Pharmacodynamics | 1 |
| PHA 7939 | Journal Colloquy in Pharmacodynamics | 1 |
Pharmacology Courses
| Code | Title | Credits |
|---|---|---|
| GMS 6563 | Molecular Pharmacology | 1-3 |
| GMS 6590 | Seminar in Pharmacology | 1 |
| GMS 6592 | Ion Channels Journal Club: Pharmacology, Biophysics, and Neuroscience of Excitable Membranes | 1 |
| GMS 6847 | Translational Research and Therapeutics: Bench, Bedside, Community, & Policy | 3 |
| GMS 7593 | Topics in Pharmacology and Toxicology | 1-3 |
Medicinal Chemistry Departmental Courses
| Code | Title | Credits |
|---|---|---|
| PHA 6354 | Natural Medicinal Products | 3 |
| PHA 6356 | Structure Determination of Complex Natural Products | 3 |
| PHA 6357 | Herbal & Dietary Supplements | 3 |
| PHA 6416 | Pharmaceutical Analysis I | 3 |
| PHA 6417 | Pharmaceutical Analysis II | 3 |
| PHA 6425 | Drug Biotrans and Molecular Mechanisms of Toxicity | 3 |
| PHA 6432 | Fundamentals of Pharmaceutical Chemistry | 1 |
| PHA 6435 | Biosynthetic Logic of Medicinal Natural Products | 3 |
| PHA 6444 | Pharmaceutical Chemistry I | 3 |
| PHA 6447 | Drug Design | 3 |
| PHA 6448 | High Throughput Drug Discovery | 2 |
| PHA 6467C | Drug Design II | 3 |
| PHA 6471 | Synthetic Medicinal Chemistry | 3 |
| PHA 6472 | Organic Synthesis of Drug Molecules | 3 |
| PHA 6476 | Advanced Combinatorial Chemistry in Drug Discovery | 3 |
| PHA 6534 | Toxicology of Chemical Weapons | 3 |
| PHA 6535 | Principles of Nucleotide Activity | 2 |
| PHA 6543 | Pharmaceutical Chemistry II | 3 |
| PHA 6556 | Introduction to Clinical Toxicology | 3 |
| PHA 6557 | Clinical Toxicology 1 | 3 |
| PHA 6840 | Medicinal Chemistry of Drugs of Abuse | 3 |
| PHA 6850 | Principles of Forensic Science | 3 |
| PHA 6851 | Forensic Analysis of DNA | 3 |
| PHA 6852 | Mammalian Molecular Biology | 3 |
| PHA 6853 | Biological Evidence and Serology | 3 |
| PHA 6854 | Forensic Immunology | 3 |
| PHA 6855 | Forensic Genetics | 3 |
| PHA 6856 | Blood Spatter and Distribution | 3 |
| PHA 6857 | Forensic Analysis of DNA 2 | 3 |
| PHA 6861 | Intro to Forensic Medicine 2 | 4 |
| PHA 6905C | Research Procedures in Medicinal Chemistry | 1-4 |
| PHA 6910 | Supervised Research | 1-5 |
| PHA 6934 | Seminar in Medicinal Chemistry | 1 |
| PHA 6935 | Selected Topics in Pharmacy | 1-4 |
| PHA 6936 | Advanced Topics in Pharmaceutical Sciences | 1-2 |
| PHA 6938 | Research Seminar | 1 |
| PHA 6940 | Supervised Teaching | 1-5 |
| PHA 6971 | Research for Master's Thesis | 1-15 |
| PHA 7979 | Advanced Research | 1-12 |
| PHA 7980 | Research for Doctoral Dissertation | 1-15 |
College of Pharmacy Courses
| Code | Title | Credits |
|---|---|---|
| PHA 6356 | Structure Determination of Complex Natural Products | 3 |
| PHA 6418 | Model-Informed Drug Development | 3 |
| PHA 6471 | Synthetic Medicinal Chemistry | 3 |
| Code | Title | Credits |
|---|---|---|
| GMS 6951 | Teaching Biomedical Science | 2 |
| GMS 6952 | Curricular Models for Biomedical Science | 3 |
| GMS 6953 | Art and Science of Mentoring | 1 |
| GMS 6954 | Assessing Effectiveness of Biomedical Science Teaching and Curricula | 3 |
| PHA 6051 | Principles of Community Engagement Research for Health Equity | 2 |
| PHA 6134 | Foundations in Precision Medicine: Genomic Technologies | 1 |
| PHA 6135 | Clinical Applications of Precision Medicine: Pharmacogenomics | 2 |
| PHA 6136 | Clinical Applications of Precision Medicine: Oncology | 2 |
| PHA 6427 | Pharmacogenetics of Drug Metabolism | 2 |
| PHA 6449 | Pharmacogenomics | 3 |
| PHA 6476 | Advanced Combinatorial Chemistry in Drug Discovery | 3 |
| PHA 6613 | Clinical Applications Precision Medicine: Precision Health | 3 |
| PHA 6630 | Medication Therapy Management: A Hematologic Focus | 3 |
| PHA 6631 | Foundations of Medication Therapy Management I | 3 |
| PHA 6632 | Foundations of Medication Therapy Management II | 3 |
| PHA 6633 | Medication Therapy Management: A Cardiovascular Focus | 3 |
| PHA 6634 | Medication Therapy Management: An Endocrine Focus | 3 |
| PHA 6635 | Medication Therapy Management: A Renal Focus | 3 |
| PHA 6636 | Medication Therapy Management: A Gastrointestinal Focus | 3 |
| PHA 6637 | Medication Therapy Management: A Psychiatric Focus | 3 |
| PHA 6638 | Medication Therapy Management: A Neurologic Focus | 3 |
| PHA 6639 | Medication Therapy Management: A Respiratory Focus | 3 |
| PHA 6746 | Patient Education and Communication in the Era of Precision Medicine | 1 |
| PHA 6910 | Supervised Research | 1-5 |
| PHA 6935 | Selected Topics in Pharmacy | 1-4 |
| PHA 6936 | Advanced Topics in Pharmaceutical Sciences | 1-2 |
| PHA 6938 | Research Seminar | 1 |
| PHA 6940 | Supervised Teaching | 1-5 |
| PHA 6950 | Precision Medicine Conference | 1 |
| PHA 6971 | Research for Master's Thesis | 1-15 |
| PHA 7979 | Advanced Research | 1-12 |
| PHA 7980 | Research for Doctoral Dissertation | 1-15 |
Pharmaceutical Sciences (MSP)- Medicinal Chemistry - Forensic Sciences, Pharmaceutical Chemistry, Clinical Toxicology
SLO 1 Knowledge
Identify, explain, describe, and apply comprehensive knowledge related to a specific discipline within the forensic or pharmaceutical sciences
SLO 2 Problem-Solving/Critical Thinking
Evaluate case studies associated with each course
Pharmaceutical Sciences - Medicinal Chemistry (MSP) Online
SLO 1 Knowledge
Identify, explain, describe, and apply comprehensive knowledge related to a specific discipline within the forensic or pharmaceutical sciences.
SLO 2 Problem-Solving/Critical Thinking
Evaluate case studies associated with each course.
SLO3 Communication
Demonstrate the ability to effectively convey information when talking about a topic that is related to a discipline within the pharmaceutical sciences.
Pharmaceutical Sciences - Medicinal Chemistry (MSP)
SLO 1 Knowledge
Demonstrate comprehensive knowledge related to a specific discipline within the pharmaceutical sciences