PHA 6354 Natural Medicinal Products 3 Credits

Grading Scheme: Letter Grade

Chemistry of compounds derived from plants and animals.

Catalog Program Pages Referencing PHA 6354

PHA 6356 Structure Determination of Complex Natural Products 3 Credits

Grading Scheme: Letter Grade

Rigorous structure determination of natural products, using modern spectroscopic methods. Become able to elucidate the structure of any organic small molecule.

Prerequisite: CHM 5235 or consent of instructor.

Catalog Program Pages Referencing PHA 6356

PHA 6357 Herbal & Dietary Supplements 3 Credits

Grading Scheme: Letter Grade

Herbal Dietary supplements are extensively used by consumers. This course provides an overview of commonly used supplements to assist healthcare practitioners in providing patients with adequate counseling to avoid drug interactions and false claims.

Catalog Program Pages Referencing PHA 6357

PHA 6416 Pharmaceutical Analysis I 3 Credits

Grading Scheme: Letter Grade

Theory and applications of relevant analytical techniques for analysis of drugs in biological samples. Offered spring term in odd-numbered years.

Catalog Program Pages Referencing PHA 6416

PHA 6417 Pharmaceutical Analysis II 3 Credits

Grading Scheme: Letter Grade

Absorption, fluorescence, phosphorescence, and spectroanalysis of drugs and related compounds.

Catalog Program Pages Referencing PHA 6417

PHA 6425 Drug Biotrans and Molecular Mechanisms of Toxicity 3 Credits

Grading Scheme: Letter Grade

Enzymology and mechanisms of drug biotransformation pathways. Examples of drugs and other xenobiotics that exhibit toxicity related to biotransformation.

Prerequisite: introductory organic chemistry, biochemistry.

Catalog Program Pages Referencing PHA 6425

PHA 6432 Fundamentals of Pharmaceutical Chemistry 1 Credit

Grading Scheme: Letter Grade

This is a foundation course whose aims are providing an introduction to the principles of Pharmaceutical chemistry, including an understanding of drug structure-activity relationships, prediction of the physico-chemical properties of a drug, basic knowledge of the major pathways of drug metabolism, and factors that can contribute to drug-drug interactions.

Catalog Program Pages Referencing PHA 6432

PHA 6435 Biosynthetic Logic of Medicinal Natural Products 3 Credits

Grading Scheme: Letter Grade

Covers topics of biosynthesis of the major families of medical natural products, structural and biochemical understanding of their biosynthetic logic, gene cluster identification, genome mining, and production of bioactive "unnatural products" for drug discovery and development.

Prerequisite: Students are expected to have the background of Biochemistry, Enzymology, and Bioorganic Chemistry.  Or permission of instructors.

Catalog Program Pages Referencing PHA 6435

PHA 6444 Pharmaceutical Chemistry I 3 Credits

Grading Scheme: Letter Grade

Students are shown how to predict the solubilities, structure-activity relationships, basic synthesis routes for selected structures, metabolism and pharmacological activity/potency of various drug classes. In particular, anticoagulants, ACE inhibitors, glucocorticoid steroids, nitrate esters, adrenergics, cholinergics, diuretics, anesthetics, antihyperlipidemics, muscle relaxants, anxiolytics, antidepressants, sedative hypnotics and vitamins are covered.

Catalog Program Pages Referencing PHA 6444

PHA 6447 Drug Design 3 Credits

Grading Scheme: Letter Grade

Relevant disciplines and their effect on new drug development, from discovery of a new active lead compound to final refinement as a commercial product.

Prerequisite: organic chemistry, biochemistry, pharmacology, or consent of instructor.

Catalog Program Pages Referencing PHA 6447

PHA 6448 High Throughput Drug Discovery 2 Credits

Grading Scheme: Letter Grade

Introduction to combinatorial chemistry, multi-compound based technologies, and their use in screening bioassays to discover lead compounds.

Prerequisite: organic chemistry, biochemistry, or consent of instructor.

Catalog Program Pages Referencing PHA 6448

PHA 6471 Synthetic Medicinal Chemistry 3 Credits

Grading Scheme: Letter Grade

Review of acid and base properties of pharmacologically active molecules. Review of mechanisms of synthetic reactions, and their applications.

Catalog Program Pages Referencing PHA 6471

PHA 6472 Organic Synthesis of Drug Molecules 3 Credits

Grading Scheme: Letter Grade

Covers advanced topics in drug molecule synthesis, including: organic reaction mechanisms, retrosynthetic analysis, asymmetric synthesis, heterocyclic chemistry, natural product synthesis, drug design and synthesis, structure-activity relationships.  Secondary topics that will be included in this course include: anticancer/antibacterial agents, screening approaches.

Prerequisite: CHM 5224 or permission of instructor.

Catalog Program Pages Referencing PHA 6472

PHA 6476 Advanced Combinatorial Chemistry in Drug Discovery 3 Credits

Grading Scheme: Letter Grade

Designed to introduce students combinatorial chemical synthesis to fully understand the functions and mechanism of action of biopolymers for medical purpose.

Prerequisite: Students are expected to have previous knowledge on general chemistry and organic synthesis.

Catalog Program Pages Referencing PHA 6476

PHA 6534 Toxicology of Chemical Weapons 3 Credits

Grading Scheme: Letter Grade

Providing healthcare providers, first responders, and others that may be exposed to chemical weapons with an understanding of their toxicology and treatment approaches.

Catalog Program Pages Referencing PHA 6534

PHA 6535 Principles of Nucleotide Activity 2 Credits

Grading Scheme: Letter Grade

This course will be introducing the students to the chemical structure of DNA and RNA; the synthetic processes for DNA and RNA synthesis; biochemical reactions and pathways for nucleotide synthesis; DNA replication, transcription and translation; covalent and reversible interactions of nucleic acids with small molecules and proteins and an overview of techniques for the analysis of nucleic acids.

Catalog Program Pages Referencing PHA 6535

PHA 6543 Pharmaceutical Chemistry II 3 Credits

Grading Scheme: Letter Grade

Showing students how to predict the solubilities, structure-activity relationships, basic synthesis routes for selected structures, metabolism and pharmacological activity/potency of various drug classes. In particular antidiabetics, anticonvulsants, H1 and H2 antagonists, analgetics, nonsteroidal antiinflammatory drugs, hormones, antibiotics, antiviral agents, and antineoplastic agents are covered.

Catalog Program Pages Referencing PHA 6543

PHA 6556 Introduction to Clinical Toxicology 3 Credits

Grading Scheme: Letter Grade

Introducing the basic methods and procedures commonly employed in Clinical Toxicology as well as the concept of Clinical Toxicology as an interdisciplinary science within the field of healthcare.

Catalog Program Pages Referencing PHA 6556

PHA 6557 Clinical Toxicology 1 3 Credits

Grading Scheme: Letter Grade

Providing students with an understanding of the toxic effects and clinical applications of various therapeutic drug classes including cardiovascular, CNS, analgetic, anesthetic, antineoplastic, and antibiotic drugs.

Prerequisite: VME 6602

Catalog Program Pages Referencing PHA 6557

PHA 6840 Medicinal Chemistry of Drugs of Abuse 3 Credits

Grading Scheme: Letter Grade

Pharmacological effects of commonly encountered licit and illicit pharmaceutical compounds.

Catalog Program Pages Referencing PHA 6840

PHA 6850 Principles of Forensic Science 3 Credits

Grading Scheme: Letter Grade

Introducing the basic disciplines of forensic science. The course is composed of twelve modules.

Catalog Program Pages Referencing PHA 6850

PHA 6851 Forensic Analysis of DNA 3 Credits

Grading Scheme: Letter Grade

Techniques for isolation of DNA from cells. Spectroscopic techniques. Hydrodynamic and electrophoretic separation methods. Sequence determination. Statistical analysis and forensic significance.

Catalog Program Pages Referencing PHA 6851

PHA 6852 Mammalian Molecular Biology 3 Credits

Grading Scheme: Letter Grade

Focus on the principles of modern molecular biology and biochemistry and expand on the concepts you may have already encountered in other classes in this program. The content will also include the applications of experimental techniques and procedures routinely used in this field.

Catalog Program Pages Referencing PHA 6852

PHA 6853 Biological Evidence and Serology 3 Credits

Grading Scheme: Letter Grade

Overview of crime scene investigation as it pertains to biological evidence. Crime scene safety. Collecting and preserving evidence. Identifying, analyzing, and interpreting biological stains.

Catalog Program Pages Referencing PHA 6853

PHA 6854 Forensic Immunology 3 Credits

Grading Scheme: Letter Grade

Antibody formation, antigen structure. Complement mediated reactions. Hypersensitivity. Immunoelectrophoretic techniques in forensic science.

Catalog Program Pages Referencing PHA 6854

PHA 6855 Forensic Genetics 3 Credits

Grading Scheme: Letter Grade

Principles of inheritance. Genetic polymorphisms and forensic implications, population genetics and paternity testing.

Catalog Program Pages Referencing PHA 6855

PHA 6856 Blood Spatter and Distribution 3 Credits

Grading Scheme: Letter Grade

Blood spatter creation and interpretation. Recording, collection, and processing of bloodstains and blood spatter evidence.

Catalog Program Pages Referencing PHA 6856

PHA 6905C Research Procedures in Medicinal Chemistry 1-4 Credits

Grading Scheme: Letter Grade

Research Procedures in Medicinal Chemistry

PHA 6910 Supervised Research 1-5 Credits, Max 5 Credits

Grading Scheme: S/U

Supervised Research

Catalog Program Pages Referencing PHA 6910

PHA 6934 Seminar in Medicinal Chemistry 1 Credit, Max 3 Credits

Grading Scheme: Letter Grade

Weekly presentation and discussion of research reports based on college programs or literature.

Catalog Program Pages Referencing PHA 6934

PHA 6935 Selected Topics in Pharmacy 1-4 Credits, Max 12 Credits

Grading Scheme: Letter Grade

Open to all departments in the College of Pharmacy.

Catalog Program Pages Referencing PHA 6935

PHA 6936 Advanced Topics in Pharmaceutical Sciences 1-2 Credits, Max 4 Credits

Grading Scheme: Letter Grade

Written and oral presentation of research designs, protocols, papers, and critical appraisals with discussion and critical review of such topics.

Catalog Program Pages Referencing PHA 6936

PHA 6938 Research Seminar 1 Credit, Max 3 Credits

Grading Scheme: Letter Grade

Seminar required of graduate students in the College of Pharmacy.

Catalog Program Pages Referencing PHA 6938

PHA 6940 Supervised Teaching 1-5 Credits, Max 5 Credits

Grading Scheme: S/U

Supervised Teaching

Catalog Program Pages Referencing PHA 6940

PHA 6971 Research for Master's Thesis 1-15 Credits

Grading Scheme: S/U

Research for Master's Thesis

Catalog Program Pages Referencing PHA 6971

PHA 7979 Advanced Research 1-12 Credits

Grading Scheme: S/U

Research for doctoral students before admission to candidacy. Designed for students with a master's degree in the field of study or for students who have been accepted for a doctoral program. Not appropriate for students who have been admitted to candidacy.

Catalog Program Pages Referencing PHA 7979

PHA 7980 Research for Doctoral Dissertation 1-15 Credits

Grading Scheme: S/U

Research for Doctoral Dissertation

Catalog Program Pages Referencing PHA 7980