BSC 6438 R for Functional Genomics 3 Credits

Grading Scheme: Letter Grade

Introductory course to the basics of the R language and to state of the art methods for functional genomics data analysis. Students will learn how to write R scripts, choose appropriate statistical tools and how to use linux environments to analyse high-throughput genomics data.

Prerequisite: BSC2010 or BSC2011 or MCB3020 or MCB3023 or BCH4024 or CHM3218 or equivalent AND STA6166 or STA6167 or equivalent.

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BSC 6459 Fundamentals of Bioinformatics 3 Credits

Grading Scheme: Letter Grade

An introduction to the basic bioinformatics tools used in computational biology for life science research.  The course will use web-based resources that analyze gene and protein sequences as pertinent data examples.

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ENU 5626 Radiation Biology 3 Credits

Grading Scheme: Letter Grade

Effects of radiation on biological molecules, cells, and man including cancer and mutagenesis; use of radiation in treatment of disease.

Prerequisite: one year each of college biology, chemistry, and physics; permission of instructor.

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MCB 5205 Microbiology of Human Pathogens 3 Credits

Grading Scheme: Letter Grade

Surveying advanced topics and current scientific literature related to human host-pathogen interactions and microbial pathogenesis, focusing on emerging bacterial and viral pathogens as agents of human disease, biosecurity, molecular identification methods, spread of multi-drug resistance among bacterial pathogens, drug discovery and alternative treatment research.

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MCB 5252 Microbiology, Immunology, and Immunotherapeutics 4 Credits

Grading Scheme: Letter Grade

Microbiology and immunology for pharmacy students. Microorganisms and infection, control with antimicrobials, host immune response, immune disorders.

Prerequisite: CHM 2210, 2211, and consent of instructor.

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MCB 5305L Microbial Genetics and Biotechnology Laboratory 2 Credits

Grading Scheme: Letter Grade

Methods for mutagenesis, gene transfer and genetic mapping, plasmid isolation, restriction enzyme use, construction of chimeric (recombinant) plasmids, phage isolation and preparation.

Prerequisite: MCB 3023/3023L and 4303 or PCB 4522 with grade of C or higher.

MCB 5505 General Virology 3 Credits

Grading Scheme: Letter Grade

Basic information on families of viruses from humans, plants, insects, animals, and bacteria. Medical, clinical, diagnostic, biotechnological, and molecular aspects of these viruses.

Prerequisite: MCB 3020/3020L and 4203 with grade of C or higher.

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MCB 5705 Astrobiology 3 Credits

Grading Scheme: Letter Grade

Astrobiology examines the origin, evolution, and future of life in our solar system. Topics will include: planet and star formation, biosphere formation, evolutionary processes biogeochemistry, microbial adaptation to extreme environments, planetary habitability, and microbiology on the International Space Station.

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MCB 6151 Prokaryotic Diversity 3 Credits

Grading Scheme: Letter Grade

An introduction to the diversity of Bacteria and Archaea. Discussions will provide a conceptual and historical framework for understanding their 1) origin and evolution; 2) morphological, metabolic, and molecular characteristics; 3) genetic and physiological diversity; 4) importance in human/animal/plant health; and 5) roles in elemental cycling.

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MCB 6317 Molecular Biology of Gene Expression 1 Credit

Grading Scheme: Letter Grade

Synthesis, processing, transport, and translation of RNA in microorganisms and eukaryotes. Additional topics include epigenetic regulation of gene expression.

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MCB 6318 Comparative Microbial Genomics 2 Credits

Grading Scheme: Letter Grade

Methods to allow experimental scientists to efficiently use genomic and post-genomic data that is publicly available. Examples taken primarily from the field of microbial metabolism and regulation.

Prerequisite: PCB 4522 and a working knowledge of basic bioinformatic tools.

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MCB 6355 Microbial/Host Defense 1 Credit

Grading Scheme: Letter Grade

Principles of host defense to microbial invasion in a context of cellular biology involving both plants and animals.

Prerequisite: MCB 4203 and PCB 5235: Immunology or equivalents, with the minimum grade of a C.

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MCB 6417 Microbial Metabolism and Energetics 1 Credit

Grading Scheme: Letter Grade

Principles of energy and biosynthetic metabolism in aerobic and anaerobic microorganisms. Current biotechnology which incorporates these principles.

Prerequisite: MCB 4403 and BCH 4024 or CHM 3218 or equivalent.

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MCB 6424 Probiotics 3 Credits

Grading Scheme: Letter Grade

Covers the use of microorganisms to promote a healthy status in the host. This course will provide a conceptual background in microbiology and immunology for the use of microorganisms for the prevention or treatment of animal and human diseases.

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MCB 6457 Metabolic Regulation 1 Credit

Grading Scheme: Letter Grade

Environmental sensing and mechanisms of microbial response. Molecular signaling, regulation of genetic information at posttranscriptional and transcriptional levels, effects on metabolism and physiology.

Prerequisite: MCB 4403 and BCH 4024 or CHM 3218 or equivalent.

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MCB 6465 Microbial Metabolic Engineering 1 Credit

Grading Scheme: Letter Grade

Principles of anaerobic fermentation and its role in production of fuels and chemicals from various feedstocks including lignocellulosic biomass. Evaluation of methods of depolymerization of complex carbohydrate feedstocks to simple sugars for fermentation.

Prerequisite: MCB 4403 and BCH 4024 or CHM 3218 or equivalent.

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MCB 6485 Advanced Techniques in Microbiology and Cell Science 2-4 Credits, Max 4 Credits

Grading Scheme: Letter Grade

Application of advanced techniques to experimental research in biochemistry, cell biology, and microbiology.

Prerequisite: consent of instructor.

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MCB 6656 Environmental Microbiology 3 Credits

Grading Scheme: Letter Grade

Overview of microorganisms in the environment including: occurrence, abundance, and distribution; current research methodologies to decipher microbial processes and activities, marine microbial ecology, microbial interactions with the environment and practices of applied environmental microbiology.

Prerequisite: MCB 3020 or MCB 3023 with a grade of C or better.

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MCB 6670C The Microbiome 3 Credits

Grading Scheme: Letter Grade

Increase knowledge, appreciation and use of genomics pertaining to the breadth of microbial diversity across a wide variety of organisms and habitats using methods that do not require culturing of the myriad of inhabitants. Students will use tools, practice analysis and interpretation of genomic data sets to analyze different microbiomes.

Prerequisite: MCB 3020 or MCB 3023 with minimum grades of C.

MCB 6772 Advanced Topics in Cell Biology 1 Credit

Grading Scheme: Letter Grade

In each semester a specific topic in cell biology with microbiological interest will be considered in a comparative discussion of animal and plant systems.

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MCB 6781 Extremophiles 3 Credits

Grading Scheme: Letter Grade

Students will learn about the evolution, physiology, biochemistry and molecular biology of extremophiles with emphasis on archaea and their viruses. Principles of energy metabolism at the limits of life will be discussed. Research that incorporates cutting-edge techniques and biotechnology applications for using extremophiles to solve real world problems is highlighted

Prerequisite: CHM 2211 (C) & (MCB 3020 or 3023) (C) & (MCB 3020L or 3023L) (C).

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MCB 6905 Experimental Microbiology 1-8 Credits, Max 12 Credits

Grading Scheme: Letter Grade

Application of physical, chemical and biological techniques to experimental problems in microbiology. Individual laboratory study.

Prerequisite: eight credits in microbiology and cell science.

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MCB 6930 Seminar 1 Credit, Max 8 Credits

Grading Scheme: S/U

Attendance required of all graduate majors at all research presentations.

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MCB 6937 Special Topics in Microbiology 1-4 Credits, Max 12 Credits

Grading Scheme: Letter Grade

Contemporary research in a particular aspect of general microbiology.

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MCB 6940 Supervised Teaching 1-5 Credits, Max 5 Credits

Grading Scheme: S/U

Supervised Teaching

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MCB 6971 Research for Master's Thesis 1-15 Credits

Grading Scheme: S/U

Research for Master's Thesis

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MCB 7922 Journal Colloquy 1 Credit, Max 8 Credits

Grading Scheme: Letter Grade

Critical presentation and discussion of recent original articles in the microbiological literature. Attendance required.

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MCB 7979 Advanced Research 1-12 Credits

Grading Scheme: S/U

Research for doctoral students before admission to candidacy. Designed for students with a master's degree in the field of study or for students who have been accepted for a doctoral program. Not appropriate for students who have been admitted to candidacy.

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MCB 7980 Research for Doctoral Dissertation 1-15 Credits

Grading Scheme: S/U

Research for Doctoral Dissertation

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PCB 5136L Techniques in Microbial and Cell Biology 3 Credits

Grading Scheme: Letter Grade

A laboratory in experimental bacteriology and cell biology. Emphasis on experimental approaches and techniques used in study of cells and microorganisms. Experiments in microscopy, cell fractionation, metabolism, physiology, genetics, and regulation.

Prerequisite: B grade or higher in MCB 3020L, CHM 3120/3120L.

PCB 5235 Immunology 3 Credits

Grading Scheme: Letter Grade

Immune system of vertebrate animals. The cellular and molecular events involved in immune responsiveness and resistance to infectious diseases.

Prerequisite: C grade or higher in MCB 3020L.

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